Department for Internal Medicine I
Gastroenterology, Endocrinology, Infectiology and Rheumatology
Admission to the waiting list for liver transplantation (Eurotransplant) depends on the severity of the liver disease. This is calculated using the so-called MELD score (Model for End-stage Liver Disease). If you have a MELD score of more than 15, you should be put on the waiting list.
Hepatocellular carcinoma (HCC)
For liver diseases with a poor prognosis, such as hepatocellular carcinoma (HCC), the actual urgency of a liver transplant is assessed using so-called match-MELD points. According to the guidelines for liver transplantation, match-MELD points can be awarded if well-defined criteria are met.
Pre-LTx outpatient clinic
In our pre-LTx outpatient clinic we look after patients who need a liver transplant for various reasons. They are assessed for inclusion on the waiting list. We also see patients who are already on the Eurotransplant list for a liver transplant. If a patient is listed for a liver transplant, in certain cases the indication for a living liver donation or inclusion on the so-called centre list can also be evaluated.
Living liver donation is the altruistic donation of a piece of liver from a living donor. This is often possible because of the liver's strong regenerative potential.
Living liver donation for infants
Liver donation from a living donor is a long-established procedure for infants. In most cases, one parent donates the smaller, left lobe of the liver to the recipient.
Living liver donation for adults
In adults, it is usually necessary to donate the larger, right lobe of the liver to ensure that the donated organ will function adequately in the recipient.
Requirements
According to the Transplantation Act, the donor must be an adult and a person who can be shown to have a close personal relationship with the donor (e.g. first or second degree relative, fiancée, spouse, etc.). Blood type compatibility, suitable anatomical conditions and similar organ size are also required to donate. Once these requirements have been met, the next step is to ensure that the donor does not have any illnesses that would prevent them from donating. Finally, an independent ethics committee must verify the donor's altruistic intentions and approve the transplant.
The centre list includes patients who are listed for a liver transplant and meet the following criteria:
Patients are placed on the centre's list according to the urgency of the transplant based on their blood group. You may be offered an organ that is available close to a transplant centre but has not been placed elsewhere by Eurotransplant. It is then up to the centre to decide whether the organ is considered suitable for the patient.
The Eurotransplant foundation is a service organisation responsible for allocating donor organs in eight European countries. Allocation, i.e. the allocation of an organ, is based solely on medical and ethical considerations.
In the case of liver diseases with a poor prognosis, such as hepatocellular carcinoma, match-MELD points can be awarded in accordance with the guidelines for liver transplantation if well-defined criteria are met.
match-MELD points may be awarded for the following diseases:
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