Complement-mediated kidney diseases

The complement system is a key component of the human immune system. It consists of a number of proteins in the blood that are activated in a cascade during infection. This activates the immune system and leads to the labelling and eventual destruction of microorganisms and infected cells.

In recent years, overactivation of the complement system has also been linked to various kidney diseases. In the rare atypical haemolytic uremic syndrome (aHUS), uncontrolled complement activation leads to thrombotic microangiopathy (TMA) and acute renal failure. In some patients, congenital changes in certain genes are thought to be responsible for the disease. Very effective therapies have been available for this disease for a number of years. In a number of other diseases, such as membranoproliferative glomerulonephritis (MPGN), dense deposition disease or C3 glomerulonephritis, the examination of complement proteins in the blood of affected patients can help to classify the disease and select a therapy.

Cooperating clinics

In the consultation hours for complement mediated diseases, all diagnostic possibilities are used to find the best possible therapy for these rare diseases.

Consultation hours

In the consultation hour for complement-mediated diseases, all diagnostic options are utilised in order to find the best possible therapy for these rare diseases.

Outpatient consultation hours: Thursdays from 8.30 am to 12.00 pm

Appointments can be made at +49 941 944-7310

Our staff will be happy to help you make an appointment during regular office hours:

Monday to Friday between 8.00 am and 4.00 pm as well as on

Friday 8.00 am to 12.00 pm