Sex hormone deficiency

We treat hypogonadism (sex hormone deficiency) in men and women with hormone replacement therapy. Hypogonadism can be congenital or acquired. It is caused either by a condition of the pituitary gland (pituitary insufficiency) or the ovaries or testes themselves.

Ullrich-Turner syndrome in women

Ullrich-Turner syndrome in women is a congenital disorder. Affected women and girls lack an X chromosome. This prevents the ovaries from developing normally. Puberty and the onset of menstruation do not occur. Those affected are usually infertile. Hormone replacement therapy induces puberty and triggers the development of secondary female sexual characteristics.

Klinefelter's syndrome in men

Men with Klinefelter's syndrome have an extra X chromosome. As a result, the testicles do not develop properly and sperm are not produced. Testosterone is not produced. The external sex organs remain small. Treatment involves lifelong replacement of testosterone (substitution), preferably from puberty. In some cases, the desire to have children can be fulfilled if small amounts of sperm are produced, which can be obtained through a pap smear. In most cases, however, the patients are infertile.

The organs that produce sex hormones can also become dysfunctional only later in life. There are many reasons for this, such as surgery or radiation therapy, infections, autoimmune diseases, etc.